Quantifying Plantar Flexor Muscles Stiffness During Passive and Active Force Generation Using Shear Wave Elastography in Individuals With Chronic Stroke.

OBJECTIVES: This study aims to investigate the mechanical properties of paretic and healthy plantar flexor muscles and assesses the spatial distribution of stiffness between the gastrocnemius medialis (GM) and lateralis (GL) during active force generation. METHODS: Shear wave elastography measurements were conducted on a control group (CNT, n=14; age=59.9±10.6 years; BMI=24.5±2.5 kg/m2) and a stroke survivor group (SSG, n=14; age=63.2±9.6 years; BMI=23.2±2.8 kg/m2). Shear modulus within the GM and GL was obtained during passive ankle mobilization at various angles of dorsiflexion (P0 =0°; P1=10°; P2=20°; P3=-20° and P4=-30°) and during different levels (30%, 50%, 70%, 100%) of maximal voluntary contraction (MVC). Muscle activations of GM, GL, soleus and tibialis anterior were also evaluated. RESULTS: The results revealed a significant increase in passive stiffness within the paretic plantar flexor muscles under high tension during passive mobilization (p<0.05). Yet, during submaximal and maximal MVC, the paretic plantar flexors exhibited decreased active stiffness levels (p<0.05). A notable discrepancy was found between the stiffness of the GM and GL, with the GM demonstrating greater stiffness from 0° of dorsiflexion in the SSG (p<0.05), and from 10° of dorsiflexion in the CNT (p<0.05). No significant difference in stiffness was observed between the GM and GL muscles during active condition. CONCLUSION: Stroke affects the mechanical properties differently depending on the state of muscle activation. Notably, the distribution of stiffness among synergistic plantar flexor muscles varied in passive condition, while remaining consistent in active condition.

Dataset of Inter and intramuscular variability of stiffness in paretic individuals during prone and standing positions.

Several studies have investigated muscle rigidity using SWE. However, the assessments may not consider the most affected regions within the same muscle tissue nor the intramuscular variability of rigidity between muscles of the same muscle group, e.g., plantar flexors. The data presented in this article aimed to explore the inter-and intramuscular variability of plantar flexors stiffness during prone and standing positions at different muscle lengths in healthy and paretic individuals. Shear wave ultrasound images were acquired for the three plantar flexor muscles (gastrocnemius medialis [GM], gastrocnemius lateralis [GL], and soleus [SOL]) in two positions: prone and standing. The imaging was conducted at various dorsiflexion angles (0°, 10°, and 20°), and measurements were taken at different proximo-distal regions within each muscle. This data set allowed us to highlight the impact of stroke on mechanical properties that varies depending on whether ankle muscles are in an active or passive state during dorsiflexion. Additionally, the modification of the ankle muscle state influences the distribution of stiffness both within and between the plantar flexors.

Spatial distribution of stiffness between and within muscles in paretic and healthy individuals during prone and standing positions.

This study investigated the inter- and intramuscular variability of plantar flexors stiffness during prone and standing positions at different muscle lengths in healthy and paretic individuals. To access tissue stiffness, shear wave elastography (SWE) measurements were carried out on two groups: control group (CG; n=14; age 43.9±9.6 years; body mass index [BMI]=24.5±2.5 kg/m2) and stroke survivor group (SSG; n=14; age 43.9±9.6 years; BMI=24.5±2.5 kg/m2). Shear Modulus (µ, kPa) within three plantar flexors (the gastrocnemius medialis [GM], gastrocnemius lateralis [GL], and soleus [SOL]) was obtained during two conditions: prone and standing position, at different angles of dorsiflexion (0°, 10°, and 20°). Measurements were also performed in different proximo-distal regions of each muscle. Muscle activation of the GM, GL, SOL, and tibialis anterior were evaluated during the two conditions. Results showed a high spatial stiffness variability between and within plantar flexors during dorsiflexion. The highest stiffness was observed in the GM, especially in the distal region at 20° in healthy and paretic muscles. In the prone position, the paretic muscle exhibits greater stiffness compared to the healthy muscle (p < 0.05). In contrast, in the standing position, an increase of stiffness in the healthy muscle compared to the paretic muscle was observed (p < 0.05). Thus, mechanical properties are differently affected by stroke depending on active and passive states of ankle muscles during dorsiflexion. In addition, the modification of ankle muscle state change stiffness distribution between and within plantar flexors.